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	<title>Comments on: Bioinformatics, multi-core CPUs and grid computing: User perspective (2/4)</title>
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	<description>Computational Biology, Epidemiology, Infectious diseases, Open Science</description>
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		<title>By: Cognitive Consonance &#187; Blog Archive &#187; Groovy/Scala/Ruby/Python on JVM</title>
		<link>http://tiago.org/ps/2007/07/17/bioinformatics-multi-core-cpus-and-grid-computing-user-perspective-24/comment-page-1/#comment-33444</link>
		<dc:creator>Cognitive Consonance &#187; Blog Archive &#187; Groovy/Scala/Ruby/Python on JVM</dc:creator>
		<pubDate>Thu, 27 Nov 2008 17:58:27 +0000</pubDate>
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		<description>[...]  Bioinformatics, multi-core CPUs and grid computing: User perspective (2/4) [...]</description>
		<content:encoded><![CDATA[<p>[...]  Bioinformatics, multi-core CPUs and grid computing: User perspective (2/4) [...]</p>
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		<title>By: Perfect Storm &#187; Blog Archive &#187; Groovy/Scala/Ruby/Python on JVM</title>
		<link>http://tiago.org/ps/2007/07/17/bioinformatics-multi-core-cpus-and-grid-computing-user-perspective-24/comment-page-1/#comment-4061</link>
		<dc:creator>Perfect Storm &#187; Blog Archive &#187; Groovy/Scala/Ruby/Python on JVM</dc:creator>
		<pubDate>Sun, 24 Feb 2008 20:22:30 +0000</pubDate>
		<guid isPermaLink="false">http://tiago.org/ps/2007/07/17/bioinformatics-multi-core-cpus-and-grid-computing-user-perspective-24/#comment-4061</guid>
		<description>[...]  Bioinformatics, multi-core CPUs and grid computing: User perspective (2/4) [...]</description>
		<content:encoded><![CDATA[<p>[...]  Bioinformatics, multi-core CPUs and grid computing: User perspective (2/4) [...]</p>
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		<title>By: Bo Peng</title>
		<link>http://tiago.org/ps/2007/07/17/bioinformatics-multi-core-cpus-and-grid-computing-user-perspective-24/comment-page-1/#comment-2140</link>
		<dc:creator>Bo Peng</dc:creator>
		<pubDate>Thu, 13 Dec 2007 17:21:40 +0000</pubDate>
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		<description>As the author of simuPOP, I have basically given up the MPI version of simuPOP and I am actively researching openMP. The reasons are:

1. It is difficult to MPIify a scripting language (but doable).
2. The mating process is hard to parallelize. It is doable but the performance gain is questionable.
3. The major reason for a MPI version is for simulating huge populations, but this is not a bug problem with 64bit computers, and 4G ram as standard (highend) configuration for 32bit machines.
4. OpenMP can make better use of multi-core, mutlti-thread CPUs than MPI.

We can discuss this further in the simuPOP mailing list.</description>
		<content:encoded><![CDATA[<p>As the author of simuPOP, I have basically given up the MPI version of simuPOP and I am actively researching openMP. The reasons are:</p>
<p>1. It is difficult to MPIify a scripting language (but doable).<br />
2. The mating process is hard to parallelize. It is doable but the performance gain is questionable.<br />
3. The major reason for a MPI version is for simulating huge populations, but this is not a bug problem with 64bit computers, and 4G ram as standard (highend) configuration for 32bit machines.<br />
4. OpenMP can make better use of multi-core, mutlti-thread CPUs than MPI.</p>
<p>We can discuss this further in the simuPOP mailing list.</p>
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