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	<title>Comments on: Evolution is a route to genetic stability</title>
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	<link>http://tiago.org/ps/2007/10/03/evolution-is-a-route-to-genetic-stability/</link>
	<description>Computational Biology, Epidemiology, Infectious diseases, Open Science</description>
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		<title>By: On computer viruses and viruses</title>
		<link>http://tiago.org/ps/2007/10/03/evolution-is-a-route-to-genetic-stability/comment-page-1/#comment-308</link>
		<dc:creator>On computer viruses and viruses</dc:creator>
		<pubDate>Fri, 05 Oct 2007 18:27:10 +0000</pubDate>
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		<description>[...] the same time that Tiago pointed here and here about the genome stability, what about the code stability of this highly technological [...]</description>
		<content:encoded><![CDATA[<p>[...] the same time that Tiago pointed here and here about the genome stability, what about the code stability of this highly technological [...]</p>
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		<title>By: Perfect Storm &#187; Blog Archive &#187; Cheap philosophy</title>
		<link>http://tiago.org/ps/2007/10/03/evolution-is-a-route-to-genetic-stability/comment-page-1/#comment-304</link>
		<dc:creator>Perfect Storm &#187; Blog Archive &#187; Cheap philosophy</dc:creator>
		<pubDate>Thu, 04 Oct 2007 15:09:42 +0000</pubDate>
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		<description>[...] would like to say a few words on Paulo&#8217;s comment, there is one phrase I disagree with and that I would like to [...]</description>
		<content:encoded><![CDATA[<p>[...] would like to say a few words on Paulo&#8217;s comment, there is one phrase I disagree with and that I would like to [...]</p>
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		<title>By: Paulo</title>
		<link>http://tiago.org/ps/2007/10/03/evolution-is-a-route-to-genetic-stability/comment-page-1/#comment-303</link>
		<dc:creator>Paulo</dc:creator>
		<pubDate>Wed, 03 Oct 2007 15:32:30 +0000</pubDate>
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		<description>Genomic stability that you &quot;see&quot; in humans is just a matter of the timescale you put to it. For &quot;us&quot; the timescale is based on a range of thousands of years, while for the Plasmodium it is a matter of hours.

I understand that in your view an ideal evolutionary accomplishment would be to have a complete and defined set of genes and features, but in reality evolution (or more specifically in this case, natural selection) feeds on the balance between the stability and instability of the genome. The inherent plasticity of each genome is the only way to adapt and evolve.

Genetic evolution is not only mutation and not all mutations are bad. Of course the evolution (or change) by means of mutations in human is obscured by other phenomena such as drift, assortative matings, among others. And for a Plasmodium mutation is not the only way they can evolve and survive. The same factors that drive &quot;ours&quot;, drive theirs. &quot;like a body that can bend, a muscle that can grow larger&quot; which are in most cases defined by the genotype. 

You can only fight the environment with the tools the genome has given you.


PS: Os nomes de especies, mesmo as mais conhecidas (E. coli, etc) seguem um padrao de nomenclatura o qual requer que o genero seja escrito iniciando-se com letra maiuscula. Usualmente nomes de especies devem ser em italicos tambem, mas esse e uma norma que pode nao ser respeitada para o caso de algumas especies, e em discussoes mais informais.</description>
		<content:encoded><![CDATA[<p>Genomic stability that you &#8220;see&#8221; in humans is just a matter of the timescale you put to it. For &#8220;us&#8221; the timescale is based on a range of thousands of years, while for the Plasmodium it is a matter of hours.</p>
<p>I understand that in your view an ideal evolutionary accomplishment would be to have a complete and defined set of genes and features, but in reality evolution (or more specifically in this case, natural selection) feeds on the balance between the stability and instability of the genome. The inherent plasticity of each genome is the only way to adapt and evolve.</p>
<p>Genetic evolution is not only mutation and not all mutations are bad. Of course the evolution (or change) by means of mutations in human is obscured by other phenomena such as drift, assortative matings, among others. And for a Plasmodium mutation is not the only way they can evolve and survive. The same factors that drive &#8220;ours&#8221;, drive theirs. &#8220;like a body that can bend, a muscle that can grow larger&#8221; which are in most cases defined by the genotype. </p>
<p>You can only fight the environment with the tools the genome has given you.</p>
<p>PS: Os nomes de especies, mesmo as mais conhecidas (E. coli, etc) seguem um padrao de nomenclatura o qual requer que o genero seja escrito iniciando-se com letra maiuscula. Usualmente nomes de especies devem ser em italicos tambem, mas esse e uma norma que pode nao ser respeitada para o caso de algumas especies, e em discussoes mais informais.</p>
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